This paper contemplates the scientific contributions of the seven winners, from the creation of the Nobel Prize to the year 2020. The laureates are Marie Curie, Irène Joliot-Curie, Dorothy Crowfoot Hodgkin, Ada Yonath, Frances Hamilton Arnold, Emmanuelle Marie Charpentier, and Jennifer Anne Doudna. In 112th editions of the Nobel Prize in Chemistry, there were 186 awards, where only seven winners were women, an amount less than 4% of the total, which makes clear the low female representation. Marie was the pioneer, being the first woman to win, alone, a Nobel Prize in Chemistry. She was the only woman to win two Nobel Prizes, and the only person awarded in two distinct scientific areas: Chemistry and Physics. Only Marie and Dorothy received the award alone, Irène, Ada and Frances shared the award with men, and Emmanuelle and Jennifer became the first pair of women to share a Nobel Prize in Chemistry. There is an evident under-representation of women in the Nobel Prize in Chemistry, but this should not be a reason not to remember and celebrate the trajectory of these brilliant scientists, who must be present in training courses in scientific areas, as well as in Basic Education schools.

HIGHLIGHTS Comparative study of the operation of eight real cases of systems installed in Paraná. There is a convergence between the values estimated by the Atlas and the ones calculated. It was possible to identify the cities that presented the greatest figures of merit.

Abstract The obtaining of electric energy from solar energy through photovoltaic systems shows great growth due to the solar potential present in the Brazilian territory. In the State of Paraná, studies are recurrent in public and private sectors on the development and performance of this technology. The installation and commissioning processes of photovoltaic plants are linked to the expectation of energy generation and the performance of the system through the figures of merit. The feasibility of the project can be confirmed when the results of these parameters are satisfactory and correspond to averages obtained from already consolidated surveys. The six photovoltaic systems implemented at the Federal Technological University of Paraná have expectations of generation and performance consistent with those of previous studies and will contribute to scientific advancement on the behavior of systems with different technologies located in different regions in the state.

This article analyzes the abstracts accepted and presented at the Coordinated Sessions of the teaching area at the Annual Meetings of the Brazilian Chemical Society. The research is characterized as qualitative of bibliographic type, having as the source of information the abstracts book of the last 10 editions (2010-2019) of the event. Through the texts, were analyzed: the amount of abstracts; year of presentation; Brazilian geographic region; number of productions by Higher Education Institutions; academic background of the first authors; thematic focus of the abstracts; level of education discussed in the abstract; and chemical knowledge present in the productions. In all, 121 abstracts were analyzed. The results indicated non-continuous production from a temporal point of view in relation to the total of abstracts, the predominance of abstracts from the Southeast region, a parity between USP and UFG institutions about the total amount of texts, and a great diversity of thematic focus, showing new research trends and the decentralization of studies focused on Chemistry Teaching. We conclude that the area of Chemistry Teaching has much to be explored, since there are still issues that are little discussed by chemical educators.

RESUMO: A presente pesquisa foi realizada a partir da articulação entre a Educação Inclusiva e o Ensino de Ciências em espaços não formais, buscando contribuir para que se ampliem as discussões no tocante à inclusão da pessoa com deficiência nos museus de Ciências incorporando ações de acessibilidade. Tendo como objetivo identificar e analisar as dimensões da Educação Inclusiva presentes/ausentes nos museus de Ciências brasileiros, foram investigadas as concepções dos coordenadores dos museus de Ciências e dos elaboradores do “Guia de Museus e Centros de Ciências Acessíveis” por meio de uma entrevista semiestruturada. Os dados foram analisados segundo a perspectiva da Análise de Conteúdo, segundo categorias definidas à priori. Observou-se que na dimensão Física há predominância dos aspectos pertinentes ao acesso à instituição. Na dimensão Programática foram identificadas ações que buscam diminuir as barreiras provenientes da falta de formação dos monitores, o que implica diretamente na mediação. Na dimensão Comunicacional foi possível identificar a criação de materiais táteis e manipuláveis. Na observação da dimensão Atitudinal, foi possível notar que as instituições têm desenvolvido práticas de sensibilização e de conscientização. Entretanto, os resultados mostram que algumas medidas ainda estão disponíveis com restrições, ou mesmo, indisponíveis. A implementação dessas mudanças deve ocorrer a curto, médio e longo prazo, visto que não é possível sanar definitivamente, todas as necessidades dos espaços e de seus visitantes. Ressaltamos a necessidade de que pesquisas futuras se dediquem a entender se a inclusão é realmente efetiva no espaço museal e como a pessoa com deficiência participa desse processo.

ABSTRACT: This research was based on the articulation between Inclusive Education and Science Teaching in non-formal spaces, seeking to contribute to the expansion of discussions regarding the inclusion of people with disabilities in Science museums, incorporating accessibility actions. Aiming to identify and analyse the dimensions of Inclusive Education present / absent in Brazilian Science museums, the conceptions of the coordinators of Science museums and the creators of the “Guide to Accessible Science Museums and Science Centers” were investigated through a semi-structured interview. The data were analysed from the perspective of Content Analysis, according to categories defined a priori. Was observed that in the Physical dimension there is a predominance of aspects relevant to access to the institution. In the Programmatic dimension, actions that seek to reduce barriers arising from the lack of training of monitors were identified, which directly implies mediation. In the Communicational dimension, it was possible to identify the creation of tactile and manipulable materials. In observing the Attitudinal dimension it was noticed that the institutions have developed practices of sensitization and awareness. However, the results show that some measures are still available with restrictions, or even, unavailable. The implementation of these changes must occur in the short, medium and long term since it is not possible to definitively address all the needs of the spaces and their visitors. We emphasize the need for future research to be dedicated to understanding whether inclusion is effective in the museum space and how the disabled person participates in this process.

RESÚMEN: Esta investigación se llevó a cabo sobre la base de la articulación entre la Educación Inclusiva y la Enseñanza de la Ciencia en espacios no formales, buscando contribuir ampliar los debates sobre la inclusión de personas con discapacidad en los museos de Ciencias. Con el objetivo de identificar y analizar las dimensiones de la Educación Inclusiva presente/ausente en los museos de Ciencias brasileños, se investigaron las concepciones de los coordinadores de los museos de Ciencias y los elaboradores de lo " Guía de Museos y Centros de Ciencias Accesibles" mediante una entrevista semiestructurada. Los datos se analizaron de acuerdo con la perspectiva del Análisis de Contenido, según las categorías definidas a priori. Se observó que en la dimensión Física predominan los aspectos pertinentes al acceso a la institución. En la dimensión Programática, se identificaron acciones que buscan reducir las barreras resultantes de la falta de capacitación de los monitores. En la dimensión Comunicacional fue posible identificar la creación de materiales táctiles. Al observar la dimensión Actitudinal, fue posible notar que las instituciones han desarrollado prácticas de concienciación. Sin embargo, los resultados muestran que algunas medidas siguen estando disponibles con restricciones, o incluso no disponibles. La implantación de estos cambios debe producirse a corto, medio y largo plazo, ya que no es posible satisfacer definitivamente todas las necesidades de los espacios y sus visitantes. Hacemos hincapié en la necesidad de que la investigación futura entienda si la inclusión es efectiva y cómo la persona discapacitada participa en este proceso.

Resumen: Objetivos: Evaluar la resistencia de unión a la microtracción en dentina humana de un sistema adhesivo universal con clorhexidina en su composición, en modo de grabado y lavado en 2 pasos, y en modo de autograbado. Metodología: 20 terceros molares divididos aleatoriamente en 4 grupos según el tipo de sistema adhesivo utilizado (Single Bond Universal®, 3MESPE y Peak Universal Bond®, Ultradent Products) y modo de uso (grabado total y autograbado). Se confeccionaron cuerpos de prueba sometidos al ensayo de microtracción utilizando una máquina de ensayos universales. Resultados: No se encontraron diferencias estadísticamente significativas entre los cuatro grupos estudiados. Conclusiones: La resistencia de unión de una resina compuesta a dentina humana no fue afectada por el uso de un sistema adhesivo universal que contiene clorhexidina en su composición aplicado en los modos de grabado total y autograbado.

Abstract: Objectives: To evaluate the microtensile bond strength to human dentin of a chlorhexidine containing universal adhesive system applied in the total-etch and self-etch modes. Methods: 20 third molars were randomly divided into 4 groups according to the universal adhesive system (Single Bond Universal ®, 3M ESPE and Peak Universal Bond®, Ultradent) and application mode used (total-etch and self-etch). Specimens were performed and subjected to a microtensile bond strength using a MTS SANS universal testing machine. Results: No statistically significant differences were found in the microtensile bond strength between the four groups studied. Conclusions: The bond strength of a composite resin to human dentin was not affected by the use of a universal adhesive system containing chlorhexidine in its composition applied in the total-etch and self-etch mode.

Sumário: Objetivos: Avaliar a resistência de união á microtração na dentina humana de um sistema adesivo universal com clorexidina na sua composição, no modo de condicionamento total em dois passos e no modo autocondicionante. Metodologia: 20 terceiros molares foram divididos aleatoriamente em 4 grupos, de acordo com o tipo de sistema adesivo utilizado (Single Bond Universal®, 3MESPE e Peak Universal Bond®, Ultradent Products) e modo de uso (condicionamento total e autocondicionante). Os corpos de prova criados foram submetidos ao teste de microtração utilizando uma máquina de ensaios universal. Resultados: Não foram encontradas diferenças estatisticamente significativas entre os quatro grupos estudados. Conclusões: A resistência de união da resina composta à dentina humana não foi afetada pelo uso de um sistema adesivo universal contendo clorexidina em sua composição, aplicado nos modos de condicionamento total ou autocondicionamento.

Resumen: La deficiencia de hierro es la causa más frecuente de anemia en pediatría. Su detección precoz, tratamiento correcto y profilaxis adecuada, constituyen una prioridad sanitaria en nuestro país. Objetivo: Describir el screening de hemoglobina realizado en lactantes con edades comprendidas entre 8 y 12 meses, usuarios de un centro de atención pediátrico de Montevideo, en el período comprendido entre 2 de mayo y 31 de octubre de 2015 y evaluar factores de riesgo de anemia ferropénica presentes. Se revisaron sus historias clínicas, consignando datos epidemiológicos, antecedentes perinatales, alimentación recibida y si recibieron suplementación con hierro adecuada. Se registró si se había realizado la medición de hemoglobina por punción digital y el valor medido. Se comparó la prevalencia de factores de riesgo entre niños con y sin anemia. En el período evaluado fueron asistidos 62 niños: 3 pretérminos de 34 semanas o menos; 15 con peso al nacer menor a 3000 gramos; 42 con lactancia materna exclusiva durante 6 meses; 54 con alimentación complementaria adecuada; 45 con suplementación de hierro. Se realizó la medición de hemoglobina por punción digital a 55 niños. Tenían anemia 28 niños (82 % leve). No se encontró asociación de padecer anemia con los factores de riesgo estudiados excepto el cumplimiento de la profilaxis con suplemento de hierro. Concluimos que la prevalencia de anemia en este grupo fue elevada y que la suplementación con hierro es importante para su prevención.

Abstract: Iron deficiency is the most frequent cause of anemia in pediatrics. Its early detection, correct treatment and adequate prophylaxis, constitute a health priority in our country. Objective: Describe the hemoglobin screening performed in infants aged between 8 and 12 months, users of a pediatric care center from Montevideo, in the period covered between May 2 and October 31, 2015 and evaluate factors of Risk of iron deficiency anemia present. Their clinical histories were reviewed, including epidemiological data, perinatal records, and diet received and if they received adequate iron supplementation. It was recorded if the hemoglobin measurement had been performed by digital puncture and the measured value. The prevalence of risk factors among children with and without anemia was compared. In the evaluated period, 62 children were assisted: 3 preterm subjects of 34 weeks or less; 15 birth weight less than 3,000 grams; 42 exclusive breastfeeding for 6 months; 54 adequate complementary feeding; 45 iron supplementation. The hemoglobin was measured by digital puncture to 55 children. 28 of them had anemia (82 % mild). No association of anemia was found with the risk factors studied except compliance with prophylaxis with iron supplementation. We conclude that the prevalence of anemia in this group was high and that iron supplementation is important for its prevention.

Resumo: A deficiência de ferro é a causa mais frequente de anemia em pediatria. Sua detecção precoce, tratamento correto e profilaxia adequada constituem uma prioridade de saúde em nosso país. O objetivo do presente trabalho é descrever a prevalência de anemia em um centro de atendimento de primeiro nível e os fatores de risco associados. Foi realizado um estudo observacional, descritivo, retrospectivo, incluindo crianças entre 8 e 12 meses de idade, que receberam controle sanitário entre maio e outubro de 2015. Suas histórias clínicas foram revisadas, incluindo dados epidemiológicos, registros perinatais e dieta recebida. e se receberam suplementação adequada de ferro. Foi registrado se a medição de hemoglobina foi realizada por punção digital e o valor medido. A prevalência de fatores de risco entre crianças com e sem anemia foi comparada. No período avaliado, 62 crianças foram atendidas: 3 prematuros de 34 semanas ou menos; 15 peso ao nascer inferior a 3000 g; 42 amamentação exclusiva por 6 meses; 54 alimentação complementar adequada; 45 suplementação de ferro. A hemoglobina foi medida por punção digital para 55 crianças. Eles tiveram 28 crianças anemia (82 % leve). Não foi encontrada associação de anemia com os fatores de risco estudados, exceto a adesão à profilaxia com suplementação de ferro. Conclui-se que a prevalência de anemia nesse grupo foi alta e que a suplementação de ferro é importante para sua prevenção.

Abstract Paper aims This paper presents an analysis of professional education programs on Supply Chain Management (SCM). The purpose of this study is to analyze six professional education programs offered by the leading SCM associations, including Advanced Certified Professional Forecaster, Certified Production and Inventory Management, Certified Professional in Supply Management, and Supply Chain Professional. The analysis of professional education programs shall consider relevant criteria. There are multiple relevant criteria; some are tangible, and some others are intangible. Originality In 2007 Prof. Lummus researched professional education influence to SCM practices. This work is an extension of Prof. Lummus research, updating it, including more professional education programs and analyzing with AHP. Research method This paper applied the Analytic Hierarchy Process (AHP), a method for multi-criteria analysis, considering individual benefits and organizational benefits as the two main criteria, and professional education programs as alternatives. Main findings The two major contributions of this paper are: first, it presents individual benefits and organizational benefits that must be met by professional education programs; second, it evaluates the programs from multiple perspectives. Implications for theory and practice The approach proposed evaluates both tangible and intangible benefits of the programs.

Abstract: Humanity is increasingly dependent on energy, which demand grows every year. Renewable energy sources are consolidated alternatives in the market, previously installed on a small scale but now thought as large plants. The correct operation, taking full advantage of the generation potential, depends on studies of the place of implantation, such as radiation levels, temperature, latitude, etc. Two photovoltaic systems installed in the city of Curitiba were studied in order to monitor their respective performances through figures of merit.

RESUMO: O objetivo deste trabalho foi determinar, em cadáveres de cães, o melhor tempo para fixação em álcool etílico (AE) e conservação em solução aquosa de cloreto de sódio (SACS) a 30% visando o treinamento microcirúrgico. Cadáveres de cinco grupos (G1 a G5) foram fixados com AE e colocados em caixas contendo AE por 30 (G2), 60 (G3), 90 (G4) ou 120 days (G5). Depois, cada grupo foi conservado em SACS 30% por 120 dias. O grupo controle (G1) foi composto de cães sem fixação/conservação. Ao final de cada período, 2 fragmentos da veia jugular externa por cadáver foram coletados para o teste de tração. Imediatamente após a coleta, as veias femorais foram avaliadas (por 2 pessoas) em relação à qualidade da sutura em microscópio cirúrgico binocular, e atribuídos escores de 0 (péssimo) à 5 (excelente), em relação às amostras frescas. A média da força máxima de ruptura no G3 no final da fixação (21,51N), assim como a média do G2 no final da conservação (21,62N) foram as que mais se mantiveram próxima do grupo controle (19,98N) e o G2 foi o grupo com o melhor escore para treinamento da sutura venosa. O AE foi eficiente como fixador assim como a SACS foi efetiva na conservação de cadáveres de cães. A pequena alteração nos valores do teste de tração, junto com o melhor escore para sutura, indicaram o grupo mantido por 30 dias em AE e SACS (G2) como o melhor para treinamento venoso microcirúrgico.

ABSTRACT: The objective of this research was to determine in necropsied dogs the best time for fixation in ethylic alcohol (EA) and preservation in 30% sodium chloride aqueous solution (SCAS 30%), aiming micro-surgical training. Five groups of necropsied dogs (G1 to G5) were fixed with EA, and put in boxes containing EA for 30 (G2), 60 (G3), 90 (G4) or 120 days (G5). After that, each group was preserved in SCAS 30% for 120 days. The control group (G1) was composed by cadavers without fixation/preservation. At the end of each period, two fragments of external jugular vein per cadaver were collected, for traction test. Immediately after the collection, the cadavers femoral veins were evaluated (by 2 people) regarding the suture quality in binocular surgical microscope, and attributed scores from 0 (bad) to 5 (excellent), regarding the fresh samples. The average at the maximum rupture strength of the G3 fixation end (21.51N), such as the average of the G2 preserving end (21.62N) remained closer to the control group (19.98N) and the G2 was the group with the best score for venous suture training. The EA was efficient as a fixative just like SCAS as a dog cadavers’ preservative. The small change of the traction test values, together with the best suture score, indicated the group kept for 30 days in EA and SCAS (G2) as the best for venous micro-surgical training.

ABSTRACT The increase in energy demand in Brazil encourages the country to increasingly invest in generation of electric energy, where the demand for other renewable sources increases gradually because they have a lower impact on the environment. The use of Grid-Connected Photovoltaic Systems (GCPVS) is a viable solution for the country, since it presents favorable natural conditions for the use of solar energy. This study approaches the current scenario of three photovoltaic systems installed in Curitiba in 2016 and part of 2017: Green Office (GO) located in Curitiba Campus Downtown, Curitiba Campus Neoville, both of the Federal Technological University of Paraná (UTFPR), as well as a residence. By means of performance parameters, performance analysis of these systems were carried out and, in order to measure the length of time of the return of the initial investment in its installation, a study of the economic viability of these systems according to the current rate model in Brazil through economic engineering tools was carried out: Simple Payback and Discounted Payback, Net Present Value and Internal Rate of Return. Finally, the application of the saved value of electric energy bills was simulated in a bank account during the system´s lifespan.

ABSTRACT This study analyzed seasonal variations in the testes, the concentration of sex hormones, the parameters of fresh and thawed semen, and the sexual behavior of male Alpine goats from a temperate region in a tropical climate and possible interference with fertility. The maximum and minimum temperature and luminosity were recorded daily, while seminal, hormonal, and behavioral assessments were carried out every fortnight. The maximum and minimum temperature (°C) and luminosity (h) were recorded daily always at 17.00 h. The scrotal circumference (cm), testicular volume (mL), volume (mL), appearance (creamy, milky, aqueous) and coloration (white, white-yellowish, and yellowish) seminal, turbulence or mass movement (0 to 5), progressive spermatic motility (0 to 100%), spermatic force (0 to 5), concentration (spermatozoids/mL), spermatic pathologies, hypoosmotic test (%), serum levels of FSH (mUI/mL), LH (mUI/mL), testosterone (ng/mL), and sexual behaviors were carried out every fortnight. There was a difference between the scrotal circumference evaluated monthly, testicular volume, volume and concentration of fresh semen, sperm vigor of the thawed semen, serum levels of testosterone, FSH and LH, and some sexual behaviors. Thus, the changes that occur in the quantity and quality of sperm, in the hormonal profile, and in sexual behaviors should not be regarded as an impediment to the use of male Alpine goats in tropical climates throughout the year. These variations do not lead to changes in the semen that may compromise the fertility of these animals.

RESUMO: Objetivou-se, com a pesquisa, avaliar os efeitos clínicos e microscópicos da associação do omento de coelho com a membrana amniótica (AM) canina, na ceratoplastia lamelar em coelhos. Dois grupos foram constituídos: um recebeu enxerto de omento alógeno livre, recoberto por AM (grupo OM- graft); o outro recebeu enxerto de AM contendo células mesenquimais derivadas do omento (grupo OM-cell). Manifestações clínicas foram avaliadas em diferentes tempos de pós-operatórios. Após as avaliações clínicas, coelhos foram submetidos à eutanásia e córneas foram colhidas para histopatologia e imunohistoquímica (Ki-67, marcador de proliferação). Relativamente às manifestações clínicas, ambos os grupos apresentaram sinais de quemose, blefarospasmo, secreção ocular, hiperemia e opacidade/edema. Neovascularização foi observada no grupo OM-cell. Avaliações à histopatologia mostraram que uma amostra de OM-cell apresentou ilhas de epitélio dentro do estroma. Aos 30 dias de pós-operatório, observou-se reepitelização corneal completa, em OM-graft e OM-cell. O grupo OM-cell apresentou mais células positivas para Ki-67. O omento livre e suas células, associados à AM, contribuíram para a reparação corneal, que se completou após 30 dias de ceratoplastia lamelar.

ABSTRACT: The objective of this research was to evaluate the clinical and microscopic effects in rabbits of lamellar keratoplasty using allogeneic omentum associated with canine amniotic membrane (AM). Rabbits were divided into two groups: one received the allogeneic free omental graft covered with the AM (OM-graft group), while the other received the AM graft containing omental mesenchymal cells (OM-cell group). Clinical signs were evaluated on different postoperative days. After the clinical assessments, the rabbits were euthanized and their corneas were obtained for histopathology and immunohistochemistry (Ki-67, marker for proliferation). Both groups showed chemosis, blepharospasm, eye discharge, hyperemia, and corneal opacity/edema. Neovascularization was observed in the OM-cell group. Histopathological evaluation revealed epithelial islands within the stroma of OM-cell samples. Thirty days after surgery, complete corneal re-epithelialization had occurred in both groups. The OM-cell group showed more Ki-67 positive cells. The free omentum and its cells, combined with the AM, contributed to corneal repair, a process that was completed 30 days after lamellar keratoplasty.

Resumo: Feridas de grandes extensões, com perda da viabilidade tecidual e retardo na cicatrização por segunda intenção são casos que se faz necessário o emprego de técnicas cirúrgicas reconstrutivas. O plasma rico em plaquetas (PRP) é um produto com maior concentração plaquetária, adjuvante no processo cicatricial de cirurgias reconstrutivas, auxiliando nos processos de hemostasia e estimulação da angiogênese. Dessa forma, delineou-se um estudo a fim de avaliar a eficácia do uso do gel produzido a partir do plasma rico em plaquetas (PRP) em flapes de avanço de padrão axial toracodorsal em coelhos, para avaliar a possibilidade de favorecer a integração do retalho no leito receptor. Utilizaram-se 30 coelhos da raça Nova Zelândia branco, separados em dois grupos de 15 animais, compreendendo os grupos plasma rico em plaquetas (GPRP), na qual empregou-se o gel antes da síntese da ferida cirúrgica, e controle (GC), na qual utilizou-se apenas solução fisiológica. Para obtenção do PRP, coletou-se sangue dos animais, e determinou-se a contagem plaquetária antes da preparação do gel. No início e término do experimento os animais foram pesados para posterior análise de ganho peso médio. Após o procedimento cirúrgico iniciou-se as avaliações macroscópicas no 3º, 7º e 14º dia, e avaliou-se presença ou ausência de exsudato, integridade da pele, edema, rubor e necrose. Após esta etapa, coletou-se o material da ferida cirúrgica para confecção das lâminas histológicas e posterior avaliação microscópica. Avaliou-se a proliferação vascular, presença de células mononucleares e polimorfonucleares, proliferação fibroblástica, colagenização, reepitelização e hemorragia. Os dados obtidos foram submetidos à análise estatística (Teste t Student, t emparalhado, e Kruskall Walis, sendo p<0,05). O ganho de peso médio não foi significativo entre os grupos; a concentração plaquetária da amostra final do PRP foi significativamente maior quando comparada com a inicial; exsudato e necrose foram significativamente maior no grupo controle quando comparado ao grupo PRP; proliferação vascular e reepitelização foram significativamente maior no grupo PRP, enquanto que a presença de mononucleares, polimorfonucleares, proliferação de fibroblastos, colagenização e hemorragia não foram significativas entre os grupos. Obteve-se no terceiro dia, diferença significativamente maior quanto à variável exsudato no grupo controle quando comparado ao grupo PRP, no sétimo dia exsudato e rubor foram significativamente maior no grupo controle, e ao décimo quarto dia exsudato e integridade da pele foram significativamente maior no grupo controle. Os resultados obtidos neste estudo evidenciaram que a utilização do plasma rico em plaquetas na forma de gel em cirurgia reconstrutiva foi capaz de estimular a angiogênese na ferida favorecendo o processo de cicatrização.

Abstract: Wounds of large tracts with loss of tissue viability and delayed healing by secondary intention are cases where it is necessary the use of reconstructive surgical techniques. The platelet rich plasma (PRP) is a product with a higher platelet concentration, adjuvant in the healing process of reconstructive surgeries, assisting in the processes of hemostasis and stimulation of angiogenesis. Thus, a study was devised to assess the efficacy of the gel produced from the platelet rich plasma (PRP) in the forward axial flaps thoracodorsal pattern in rabbits to evaluate the ability to promote the integration of the flap the recipient bed. We used 30 white rabbits New Zealand, separated into two groups of 15 animals, comprising the platelet rich plasma groups (GPRP), in which we used the gel before the synthesis of the surgical wound , and control (CG), in which only saline was used. To obtain the PRP, the blood was collected from the animals, was determined and the platelet count before preparation of the gel. At the beginning and end of the experiment the animals were weighed for analysis of average weight gain. After surgery began macroscopic in the 3rd, 7th and 14th day reviews, and we assessed the presence or absence of exudate, skin integrity, edema, redness and necrosis. After this step, yielded the material for the manufacture of surgical wound, followed by microscopic histological slides. We evaluated vascular proliferation, presence of polymorphonuclear and mononuclear cells, fibroblast proliferation, collagen deposition, reepithelialization and hemorrhage. The data were subjected to statistical analysis (Student t test, t paired, and Kruskal Wallis test, and p<0.05). The average weight gain was not significant between the groups; platelet concentration in the final sample of PRP was significantly higher when compared with the original; exudate and necrosis were significantly higher in the control group compared to PRP group, vascular proliferation and reepithelialization were significantly greater in PRP group, whereas the presence of mononuclear cells, polymorphonuclear cells, proliferation of fibroblasts, collagen and hemorrhage were not significant between groups. Obtained on the third day, as the difference significantly greater exudate variable in the control group compared to the PRP group; on the seventh day exudate and flushing were significantly higher in the control group, and the fourteenth day exudate and integrity of the skin were significantly higher in the control group. The results of this study showed that the use of platelet rich plasma gel in the form of reconstructive surgery was able to stimulate angiogenesis in the wound favoring the healing process.